Lymph node imaging in patients with primary breast cancer: Concurrent diagnostic tools Review
| Authors: | Marino, M. A.; Avendano, D.; Zapata, P.; Riedl, C. C.; Pinker, K. |
| Review Title: | Lymph node imaging in patients with primary breast cancer: Concurrent diagnostic tools |
| Abstract: | The detection of lymph node metastasis affects the management of patients with primary breast cancer significantly in terms of staging, treatment, and prognosis. The main goal for the radiologist is to determine and detect the presence of metastatic disease in nonpalpable axillary lymph nodes with a positive predictive value that is high enough to initially select patients for upfront axillary lymph node dissection. Features that are suggestive of axillary adenopathy may be seen with different imaging modalities, but ultrasound is the method of choice for evaluating axillary lymph nodes and for performing image-guided lymph node interventions. This review aims to provide a comprehensive overview of the available imaging modalities for lymph node assessment in patients diagnosed with primary breast cancer. Implications for Practice: The detection of lymph node metastasis affects the management of patients with primary breast cancer. The main goal for the radiologist is to detect lymph node metastasis in patients to allow for the selection of patients who should undergo upfront axillary lymph node dissection. Features that are suggestive of axillary adenopathy may be seen with mammography, computed tomography, and magnetic resonance imaging, but ultrasonography is the imaging modality of choice for evaluating axillary lymph nodes. A normal axillary lymph node is characterized by a reniform shape, a maximal cortical thickness of 3 mm without focal bulging, smooth margins, and, depending on size, a discernable central fatty hilum. © 2019 The Authors. The Oncologist published by Wiley Periodicals, Inc. on behalf of AlphaMed Press. |
| Keywords: | histopathology; review; multimodality cancer therapy; cancer staging; positron emission tomography; magnetic resonance imaging; lymph node metastasis; lymph node dissection; lymph nodes; sensitivity and specificity; computer assisted tomography; breast cancer; image analysis; clinical assessment; cancer therapy; ultrasound; axillary lymph node; mammography; lymph node; physical examination; axilla; nuclear magnetic resonance; lymphadenopathy; ultrasonography; predictive value; single photon emission computed tomography; cancer prognosis; human; priority journal; radiomics; digital breast tomosynthesis |
| Journal Title: | The Oncologist |
| Volume: | 25 |
| Issue: | 2 |
| ISSN: | 1083-7159 |
| Publisher: | Oxford University Press |
| Date Published: | 2020-02-01 |
| Start Page: | e231 |
| End Page: | e242 |
| Language: | English |
| DOI: | 10.1634/theoncologist.2019-0427 |
| PUBMED: | 32043792 |
| PROVIDER: | scopus |
| PMCID: | PMC7011661 |
| DOI/URL: | |
| Notes: | Review -- Source: Scopus |
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