Soft tissue special issue: Gnathic fibro-osseous lesions and osteosarcoma Journal Article


Authors: Hameed, M.; Horvai, A. E.; Jordan, R. C. K.
Article Title: Soft tissue special issue: Gnathic fibro-osseous lesions and osteosarcoma
Abstract: Gnathic fibro-osseous lesions are a diverse group of disease processes which share overlapping microscopic features characterized by fibroblastic stroma with variable cellularity and a range of bone forming pathological processes leading to woven, sclerotic and cementum-like structures. Some of the lesions are unique to craniofacial location and a combination of clinical, radiological and pathological correlation is often necessary for diagnostic accuracy. Gnathic osteosarcomas are rare tumors with differences in age distribution and behavior as compared to osteosarcoma of long bones. This review will discuss the clinicopathological and radiological features of gnathic fibro-osseous lesions and osteosarcoma with updates on current genetics and molecular pathogenesis. © 2020, Springer Science+Business Media, LLC, part of Springer Nature.
Keywords: osteosarcoma; fibrous dysplasia; ossifying fibroma; cemento-osseous dysplasia; cemento-ossifying fibroma; diffuse sclerosing osteomyelitis; fibro-osseous lesions; juvenile psammomatoid ossifying fibroma; juvenile trabecular ossifying fibroma
Journal Title: Head and Neck Pathology
Volume: 14
Issue: 1
ISSN: 1936-055X
Publisher: Humana Press Inc  
Date Published: 2020-03-01
Start Page: 70
End Page: 82
Language: English
DOI: 10.1007/s12105-019-01094-2
PUBMED: 31950477
PROVIDER: scopus
PMCID: PMC7021863
DOI/URL:
Notes: Article -- Export Date: 2 March 2020 -- Source: Scopus
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  1. Meera Hameed
    282 Hameed