Authors: | Bello, D. M.; Faries, M. B. |
Review Title: | The Landmark Series: MSLT-1, MSLT-2 and DeCOG (management of lymph nodes) |
Abstract: | Management of regional lymph nodes in patients with melanoma has evolved significantly in recent years. The value of nodal intervention, long utilized for its perceived therapeutic benefit, has now shifted to that of a critical prognostic procedure used to guide clinical decision making. This review focuses on the three landmark, randomized controlled trials evaluating the role of surgery for regional lymph nodes in melanoma: Multicenter Selective Lymphadenectomy Trial I (MSLT-I), German Dermatologic Cooperative Oncology Group-Selective Lymphadenectomy Trial (DeCOG-SLT), and Multicenter Selective Lymphadenectomy Trial II (MSLT-II). © 2019, Society of Surgical Oncology. |
Keywords: | cancer survival; review; cancer adjuvant therapy; lymph node metastasis; lymph node dissection; sentinel lymph node biopsy; melanoma; clinical decision making; randomized controlled trial (topic); multicenter study (topic); cancer prognosis; human |
Journal Title: | Annals of Surgical Oncology |
Volume: | 27 |
Issue: | 1 |
ISSN: | 1068-9265 |
Publisher: | Springer |
Date Published: | 2020-01-01 |
Start Page: | 15 |
End Page: | 21 |
Language: | English |
DOI: | 10.1245/s10434-019-07830-w |
PUBMED: | 31535299 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | Review -- Source: Scopus |