Metachronous renal cell carcinoma with metastasis to the urinary bladder, and distant organs, 28 years after radical nephrectomy: A case report Journal Article
| Authors: | Babar, M.; Hamdani, S.; Liu, C.; Vedula, J.; Schnapp, D. S. |
| Article Title: | Metachronous renal cell carcinoma with metastasis to the urinary bladder, and distant organs, 28 years after radical nephrectomy: A case report |
| Abstract: | Background: Metachronous renal cell carcinoma after radical nephrectomy is extremely rare. Renal cell carcinoma commonly metastasizes to distant organs. However, metastasis to the urinary bladder is very uncommon. Case presentation: Herein, we report a case of metachronous renal cell carcinoma with metastasis to the urinary bladder, left acetabulum, left rib, lungs, thyroid, right renal vein and inferior vena cava. The patient had undergone a left-sided radical nephrectomy 28 years ago. The pathological diagnosis of a fragment of the bladder tumor was consistent with Fuhrman grade 2 clear cell renal cell carcinoma. Conclusions: Although metachronous renal cell carcinoma after radical nephrectomy is rare, active surveillance should be still considered. Renal cell carcinoma has shown to unusually metastasize to the urinary bladder, a rarely reported organ of metastasis. Treatment options, such as immunotherapy, are available to patients with such metastasis and long-term survivorship can be achieved. © 2019 The Author(s). |
| Keywords: | cancer chemotherapy; clinical article; human tissue; aged; case report; sunitinib; bone metastasis; nuclear magnetic resonance imaging; computer assisted tomography; renal cell carcinoma; hematuria; nephrectomy; distant metastasis; lung metastasis; radical nephrectomy; fluorodeoxyglucose f 18; cystectomy; drug dose increase; inferior cava vein; urine retention; kidney vein; tumor necrosis; bladder metastasis; thyroid metastasis; rib; acetabulum; nivolumab; transurethral resection of the bladder; human; male; article; positron emission tomography-computed tomography; bladder distension |
| Journal Title: | BMC Urology |
| Volume: | 19 |
| Issue: | 1 |
| ISSN: | 1471-2490 |
| Publisher: | Biomed Central Ltd |
| Date Published: | 2019-01-01 |
| Start Page: | 136 |
| Language: | English |
| DOI: | 10.1186/s12894-019-0521-1 |
| PUBMED: | 31881880 |
| PROVIDER: | scopus |
| PMCID: | PMC6935093 |
| DOI/URL: | |
| Notes: | Article -- Source: Scopus |
