β-galactoside transport in E. coli: A functional dissection of lac permease Journal Article
| Authors: | Kaback, H. R.; Bibi, E.; Roepe, P. D. |
| Article Title: | β-galactoside transport in E. coli: A functional dissection of lac permease |
| Abstract: | The polytopic membrane protein lac permease harnesses energy from the electrochemical H+ gradient to transport β-galactosidases against a concentration gradient. Although high-resolution structural information is still lacking, the permease is thought to possess 12 membrane-spanning α-helical segments. Various experimental strategies, including site-directed mutagenesis, have been employed to probe the function of this membrane protein at the molecular level. © 1990. |
| Keywords: | review; nonhuman; amino acid sequence; molecular sequence data; escherichia coli; hyaluronidase; biological transport; glycosides; lactose operon; galactosides; membrane transport proteins; lactose; priority journal; lactose permease; beta galactoside |
| Journal Title: | Trends in Biochemical Sciences |
| Volume: | 15 |
| Issue: | 8 |
| ISSN: | 0968-0004 |
| Publisher: | Elsevier Inc. |
| Date Published: | 1990-08-01 |
| Start Page: | 309 |
| End Page: | 314 |
| Language: | English |
| DOI: | 10.1016/0968-0004(90)90020-c |
| PUBMED: | 2204157 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 27 January 2020 -- Source: Scopus |
