Methemoglobinemia induced by topical anesthetic (benzocaine) Journal Article


Authors: Linares, L. A.; Peretz, T. Y.; Chin, J.
Article Title: Methemoglobinemia induced by topical anesthetic (benzocaine)
Abstract: Methemoglobinemia is a condition in which more than 2% of the hemoglobin of the blood has been oxidized to the ferric form, a molecule which is incapable of binding oxygen or carbon dioxide. Clinically, the patient appears lethargic, cyanotic, and does not respond to oxygen. We describe a patient with esophageal carcinoma who developed severe methoglobinemia following application of benzocaine in spray for local anesthesia prior to intraluminal irradiation. Review of the literature is presented. © 1990.
Keywords: aged; case report; adenocarcinoma; radiotherapy; esophagus carcinoma; esophagus; esophageal neoplasms; intubation; anesthesia, local; topical anesthesia; methemoglobinemia; benzocaine; topical drug administration; human; male; priority journal; article
Journal Title: Radiotherapy and Oncology
Volume: 18
Issue: 3
ISSN: 0167-8140
Publisher: Elsevier Inc.  
Date Published: 1990-07-01
Start Page: 267
End Page: 269
Language: English
DOI: 10.1016/0167-8140(90)90062-2
PUBMED: 2217871
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 27 January 2020 -- Source: Scopus
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