Cervical lymph node metastases - Diagnostic, therapeutic, and prognostic implications Journal Article


Author: Shah, J. P.
Article Title: Cervical lymph node metastases - Diagnostic, therapeutic, and prognostic implications
Abstract: Patients with carcinoma of the upper aerodigestive tract presenting with cervical lymph node metastasis carry a poorer prognosis compared to those in whom the regional lymph nodes are uninvolved. Prognosis worsens as the volume of metastatic cancer in the cervical lymph nodes increases. While the classical treatment for these metastases has been a radical neck dissection, this operation produces significant esthetic and functional morbidity. Radiation therapy alone offers poor results when bulky disease in the neck is present. Fortunately, the combination of surgery and radiation therapy offers significant advantages, not only in terms of reduction of morbidity, but improvement of disease control. The author discusses the current debate over the extent of neck dissection and the advantages of pre- and post-operative radiation.
Keywords: mortality; laryngeal neoplasms; cancer staging; lymph node metastasis; lymphatic metastasis; neoplasm staging; risk factors; pathology; risk factor; salivary gland tumor; salivary gland neoplasms; neck; mouth neoplasms; pharynx cancer; larynx tumor; mouth tumor; pharyngeal neoplasms; prognosis; human; article
Journal Title: Oncology (Norwalk)
Volume: 4
Issue: 10
ISSN: 0890-9091
Publisher: C M P Medica LLC * The Oncology Group  
Date Published: 1990-10-01
Start Page: 61
End Page: 69; discussion 72, 76
Language: English
PUBMED: 2149826
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 27 January 2020 -- Source: Scopus
Citation Impact
MSK Authors
  1. Jatin P Shah
    722 Shah