Neoadjuvant chemotherapy in invasive bladder cancer: The evolving role of surgery Journal Article


Authors: Herr, H. W.; Whitmore, W. F. Jr; Morse, M. J.; Sogani, P. C.; Russo, P.; Fair, W. R.
Article Title: Neoadjuvant chemotherapy in invasive bladder cancer: The evolving role of surgery
Abstract: The role of an operation in patients receiving neoadjuvant chemotherapy for clinically localized but invasive transitional cell carcinoma of the bladder currently is evolving. An operation is essential for case selection and evaluation of local response but it also contributes to bladder preservation and survival. The procedure that is necessary to select for and assess response to chemotherapy may itself alter the actual or proceed to evolution of invasive bladder cancer. Neoadjuvant chemotherapy is a reasonable therapeutic strategy in selected patients but it remains to be seen whether the results will prove to be superior to those achieved with standard endoscopic and open operations.
Keywords: cancer chemotherapy; antineoplastic agent; bcg vaccine; bladder cancer; cancer invasion; short survey; transitional cell carcinoma; human; priority journal
Journal Title: Journal of Urology
Volume: 144
Issue: 5
ISSN: 0022-5347
Publisher: Elsevier Science, Inc.  
Date Published: 1990-11-01
Start Page: 1083
End Page: 1088
Language: English
DOI: 10.1016/s0022-5347(17)39664-7
PUBMED: 2231876
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 27 January 2020 -- Source: Scopus
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MSK Authors
  1. Paul Russo
    581 Russo
  2. Pramod C Sogani
    75 Sogani
  3. Harry W Herr
    594 Herr
  4. William R Fair
    342 Fair
  5. Willet F. Whitmore Jr
    139 Whitmore
  6. Michael J. Morse
    40 Morse