Central venous catheter complications in sarcoma patients receiving adjuvant chemotherapy Journal Article
| Authors: | Israel, R. J.; Magill, G. B.; Brennan, M. F. |
| Article Title: | Central venous catheter complications in sarcoma patients receiving adjuvant chemotherapy |
| Abstract: | As part of a prospective randomized study in patients with high grade soft tissue sarcoma (STS), 47 patients received post‐operative adjuvant Adriamycin. The method of administration was randomized to intravenous bolus (B) or to continuous 72 hour infusion (CI) via a Silastic right atrial catheter. Both groups received 60 mg/m2 every 3 weeks. There were nine hospital admissions for treatment related complications in four of the 26 CI patients compared to none in the 21 B patients (P = 0.03). All of the admissions related to complications involving the central venous catheter (CVC). This apparent increased risk for hospital admission secondary to treatment related complications in patients treated with CI must be considered in the planning of future therapeutic trials. Copyright © 1990 Wiley‐Liss, Inc., A Wiley Company |
| Keywords: | clinical article; doxorubicin; prospective studies; continuous infusion; sarcoma; randomized controlled trials; soft tissue sarcoma; wound infection; infusions, intravenous; intravenous drug administration; injections, intravenous; central venous catheter; catheterization, central venous; adriamycin; human; male; female; priority journal; article; intravenous bolus |
| Journal Title: | Journal of Surgical Oncology |
| Volume: | 44 |
| Issue: | 2 |
| ISSN: | 0022-4790 |
| Publisher: | Wiley Blackwell |
| Date Published: | 1990-06-01 |
| Start Page: | 100 |
| End Page: | 102 |
| Language: | English |
| DOI: | 10.1002/jso.2930440208 |
| PUBMED: | 2192197 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 27 January 2020 -- Source: Scopus |
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