Preferential selection during therapy in vivo by edatrexate compared to methotrexate of resistant L1210 cell variants with decreased folylpolyglutamate synthetase activity Journal Article


Authors: Rumberger, B. G.; Schmid, F. A.; Otter, G. M.; Sirotnak, F. M.
Article Title: Preferential selection during therapy in vivo by edatrexate compared to methotrexate of resistant L1210 cell variants with decreased folylpolyglutamate synthetase activity
Keywords: nonhuman; comparative study; methotrexate; animal cell; mouse; phenotype; animal; mice; animal experiment; drug resistance; radioisotope; neoplasm transplantation; folic acid antagonists; aminopterin; peptide synthases; leukemia l1210; edatrexate; article; support, non-u.s. gov't; support, u.s. gov't, p.h.s.; leukemia l 1210; folylpolyglutamate synthase
Journal Title: Cancer Communications
Volume: 2
Issue: 9
ISSN: 0955-3541
Publisher: Cognizant Communication Corporation  
Date Published: 1990-09-01
Start Page: 305
End Page: 310
Language: English
PUBMED: 2206778
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 27 January 2020 -- Source: Scopus
Citation Impact
MSK Authors
  1. Francis M Sirotnak
    184 Sirotnak
  2. Glenys M. Otter
    27 Otter
  3. Franz A. Schmid
    26 Schmid