Active specific immunotherapy in the treatment of patients with cancer Journal Article

  


Author: Livingston, P.
Article Title: Active specific immunotherapy in the treatment of patients with cancer
Abstract: New approaches to the construction of cancer vaccines focus on the identification and purification of immunogenic cancer antigens and on methods for increasing their immunogenicity. They include preparation of antigens by chemical synthesis or recombinant DNA technology, conjugation of carbohydrate antigens with immunogenic protein carriers to augment T-cell help, use of antiidiotypic antibodies in lieu of antigens, and development of more potent immunologic adjuvants. Against the background of recent advances in the field of antigen presentation, these approaches offer hope for improving the efficacy of cancer vaccines.
Keywords: review; antigen; immunotherapy; tumor vaccine; vaccine; cancer; human
Journal Title: Immunology and Allergy Clinics of North America
Volume: 11
Issue: 2
ISSN: 0889-8561
Publisher: Elsevier Inc.  
Date Published: 1991-05-01
Start Page: 401
End Page: 423
Language: English
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-0025892525&partnerID=40&md5=c3c3d8dd3952c179ca71c937458d42a4
Notes: Review -- Export Date: 27 September 2019 -- Source: Scopus