Image-guided volumetric modulated arc therapy (IG-VMAT) for prostate cancer Conference Paper

  

Authors:	Song, Y.; Mueller, B.; Obcemea, C.; Mychalczak, B.
Title:	Image-guided volumetric modulated arc therapy (IG-VMAT) for prostate cancer
Conference Title:	5th European Conference of the International Federation for Medical and Biological Engineering
Abstract:	Intensity modulated radiation therapy (IMRT) remains the prevailing radiation treatment modality for localized prostate cancer. However, IMRT has three pronounced deficiencies: an elevated MU, a reduced MU-to-c-Gy coefficient, and the inability to track target motion. To address these issues, we have developed a novel radiation treatment technique, called the image-guided volumetric modulated radiation therapy (IG-VMAT) for the treatment of localized prostate cancer. In IG-VMAT approach, the image-guided target localization is achieved through point-based image registration using implanted gold-seed markers as a similarity measure, MU reduction is realized by using beam aperture-based inverse optimization, and the desired dose distribution is obtained through a synergistic modulation of MLC linear speed, temporal dose rate, and LINAC gantry angular speed. Our preliminary clinical data indicate that IG-VMAT can produce equal or better treatment plans than IMRT, reduce mean beam-on time by 45.8%, and achieve 1 mm accuracy in target localization. © 2011 Springer-Verlag Berlin Heidelberg.
Keywords:	radiotherapy; prostate cancer; medical imaging; physical therapy; intensity-modulated radiation therapy; prostate cancers; diseases; rapidarc; vmat; angular distribution; radiation treatments; treatment plans; volumetric modulated arc therapy; image-guided; localized prostate cancer; dose distributions; dose rate; ig-vmat; angular speed; clinical data; inverse optimization; linear speed; point-based; similarity measure; target localization; target motions
Journal Title	IFMBE Proceedings
Volume:	37
Conference Dates:	2011 Sep 14-18
Conference Location:	Budapest, Hungary
ISBN:	1680-0737
Publisher:	Springer
Date Published:	2011-01-01
Start Page:	223
End Page:	226
Language:	English
DOI:	10.1007/978-3-642-23508-5_59
PROVIDER:	scopus
DOI/URL:	http://www.scopus.com/inward/record.url?eid=2-s2.0-80455127386&partnerID=40&md5=260762e7de8338d1073aaab0d15d0101
Notes:	ISBN: 978-3-642-23507-8 -- IFMBE Proceedings - IFMBE Proc. - "Export Date: 9 December 2011" - "Source: Scopus"

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