Isthmusectomy in selected patients with well-differentiated thyroid carcinoma Journal Article

   

Authors:	Park, H.; Harries, V.; McGill, M. R.; Ganly, I.; Shah, J. P.
Article Title:	Isthmusectomy in selected patients with well-differentiated thyroid carcinoma
Abstract:	Background: Isthmusectomy in the treatment of well-differentiated thyroid carcinoma (WDTC) is controversial. In this study, we analyze the outcomes of WDTC managed by isthmusectomy alone. Methods: Forty-three patients treated with isthmusectomy alone were identified from an institutional database of 6259 surgically treated patients with WDTC. Patient and tumor characteristics were analyzed. Disease-specific survival (DSS) and recurrence-free survival (RFS) were calculated using the Kaplan-Meier method. Results: The pT classification was T1 for 41 and T2 for two patients. All were clinical N0, but 10 pts were pN1a. Using the American Thyroid Association risk stratification system, 9 patients were low-risk and 22 were intermediate-risk. One patient developed local recurrence, and two developed regional lymph node metastases; the 5- and 10-year DSS was 100.0%. The 5- and 10-year RFS was 93.1%. Conclusions: Isthmusectomy alone is an acceptable procedure in selected patients with low- and intermediate-risk WDTC limited to the isthmus. © 2019 Wiley Periodicals, Inc.
Keywords:	adolescent; adult; cancer survival; clinical article; aged; cancer surgery; overall survival; histopathology; cancer recurrence; cancer patient; follow up; lymph node metastasis; risk assessment; recurrent disease; thyroidectomy; cancer classification; disease specific survival; thyroid surgery; recurrence free survival; thyroid follicular carcinoma; intermediate risk patient; differentiated thyroid cancer; clinical outcome; subtotal thyroidectomy; well-differentiated thyroid carcinoma; low risk patient; human; male; female; priority journal; article; isthmectomy; isthmus; isthmusectomy; low risk cancer
Journal Title:	Head & Neck
Volume:	42
Issue:	1
ISSN:	1043-3074
Publisher:	John Wiley & Sons, Inc.
Date Published:	2020-01-01
Start Page:	43
End Page:	49
Language:	English
DOI:	10.1002/hed.25968
PUBMED:	31589005
PROVIDER:	scopus
PMCID:	PMC7485011
DOI/URL:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85073967545&doi=10.1002%2fhed.25968&partnerID=40&md5=61ee950784ac3e53e94ae51d64d0721b
Notes:	Article -- Source: Scopus

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