Detecting cellular events in brain cortex using time-lapse microscopy Conference Paper
| Authors: | Ding, L.; Huang, K.; Insolera, C. R.; Shi, S. H. |
| Title: | Detecting cellular events in brain cortex using time-lapse microscopy |
| Conference Title: | 8th IEEE International Symposium on Biomedical Imaging: From Nano to Macro |
| Abstract: | We present a framework for cell tracking in a highly cluttered environment in live cell imaging from mouse brain cortex. Our goal is to track cells over a long period of time for intracellular calciumion concentration in order to detect important cellular events such as neural activity and cell division. Since traditional object tracking approach such as segmentation followed by tracking is not applicable due to the cluttered environment, we developed a pipeline featuring a combined cell tracking and segmentation scheme using particle filtering and level set based active contour methods. Our results show that we can track multiple cells with 90% of results meeting the error tolerance. © 2011 IEEE. |
| Keywords: | cell proliferation; brain cortex; brain; medical imaging; mammals; cell tracking; cells; active contour; calcium imaging; particle filter; active contours; nonlinear filtering; numerical methods |
| Journal Title | International Symposium on Biomedical Imaging. Proceedings |
| Conference Dates: | 2011 Mar 20-Apr 2 |
| Conference Location: | Chicago, IL |
| ISBN: | 1945-7928 |
| Publisher: | IEEE |
| Location: | Chicago, IL |
| Date Published: | 2011-01-01 |
| Start Page: | 1553 |
| End Page: | 1556 |
| Language: | English |
| DOI: | 10.1109/ISBI.2011.5872697 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - Proceedings - International Symposium on Biomedical Imaging - IEEE Comput. Soc. Conf. Comput. Vis. Pattern Recogn. - "Conference code: 87101" - "Export Date: 9 December 2011" - "Art. No.: 5872697" - "Sponsors: Inst. Electr. Electron. Eng., Eng. Med. Biol. Soc. (IEEE EMBS); Inst. Electr. Electron. Eng., Signal Process. Soc. (IEEE SPS)" - 30 March 2011 through 2 April 2011 - "Source: Scopus" |
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