Retroperitoneal lymph node dissection (RPLND) Journal Article


Authors: Zivanovic, O.; Sheinfeld, J.; Abu-Rustum, N. R.
Article Title: Retroperitoneal lymph node dissection (RPLND)
Abstract: Pelvic and paraaortic lymph nodes are common sites of metastases from gynecologic malignancies and may act as a sanctuary of chemoresistant tumor cells in some patients. There is no doubt that the evaluation of the regional lymph nodes provides important prognostic information for patients with gynecologic malignancies. The rationale is a more accurate assessment of the extent of disease, allowing for better individualization of adjuvant therapy. Nonetheless, the therapeutic role of systematic lymphadenectomy in patients with gynecologic malignancies is still under debate. The retroperitoneal lymph node dissection (RPLND) has been shown to prolong survival for patients with chemorefractory ovarian immature teratoma. Furthermore, RPLND is an important aspect of post-chemotherapy debulking surgery for nonseminomatous germ cell tumors, which is the counterpart of the ovarian immature teratoma. Therefore, the ability to perform an extensive RPLND is an important skill in the surgical armamentarium of the gynecologic oncologist. In the following article we outline the surgical anatomy and describe the essential steps of the RPLND. © 2008 Elsevier Inc. All rights reserved.
Keywords: cancer patient; lymph node metastasis; antineoplastic agent; lymph node dissection; paraaortic lymph node; pelvis lymph node; lymph nodes; lymphatic metastasis; lymph node excision; cytoreductive surgery; genital neoplasms, female; gynecologic surgical procedures; ovary teratoma; germ cell tumor; gynecologic cancer; surgical anatomy; retroperitoneal lymph node dissection; retroperitoneal space
Journal Title: Gynecologic Oncology
Volume: 111
Issue: 2 Suppl.
ISSN: 0090-8258
Publisher: Elsevier Inc.  
Date Published: 2008-11-01
Start Page: S66
End Page: S69
Language: English
DOI: 10.1016/j.ygyno.2008.07.043
PUBMED: 18789513
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 3" - "Export Date: 17 November 2011" - "CODEN: GYNOA" - "Source: Scopus"
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  1. Oliver Zivanovic
    291 Zivanovic
  2. Joel Sheinfeld
    254 Sheinfeld