Microwave ablation in primary lung malignancies Review


Authors: Moussa, A. M.; Ziv, E.; Solomon, S. B.; Camacho, J. C.
Review Title: Microwave ablation in primary lung malignancies
Abstract: Lung cancer is the leading cause of cancer-related mortality worldwide. Eighty-five percent of cases correspond to non-small cell lung cancer (NSCLC) and pivotal nonsurgical options for early-stage disease include percutaneous ablation and stereotactic body radiation therapy (SBRT). Microwave Ablation (MWA) is a locoregional treatment option that has many advantages over radiofrequency ablation and has been able to overcome the limitations of this technique in the treatment of early-stage NSCLC. In this review article, we highlight the current evidence supporting the use of MWA in patients with early-stage NSCLC and discuss the technical considerations of the procedure, including optimal patient selection and planning strategies, as well as the potential complications and reported outcomes. Finally, we mention future trends involving ablation in NSCLC, including its role in combination with SBRT in central tumors, management of post-SBRT local recurrence, and its potential as an adjuvant treatment option for patients with resistance to systemic therapy or in combination with checkpoint inhibitors. © 2019 Massachussetts Medical Society. All rights reserved.
Keywords: treatment outcome; primary tumor; cancer recurrence; patient selection; treatment planning; cancer patient; follow up; treatment indication; pain; pneumonia; early cancer; pneumothorax; pleura effusion; non small cell lung cancer; nsclc; microwave ablation; lung abscess; human; priority journal; article; microwave thermotherapy; primary lung tumors
Journal Title: Seminars in Interventional Radiology
Volume: 36
Issue: 4
ISSN: 0739-9529
Publisher: Thieme Publishing  
Date Published: 2019-10-01
Start Page: 326
End Page: 333
Language: English
DOI: 10.1055/s-0039-1700567
PROVIDER: scopus
PMCID: PMC6823043
PUBMED: 31680724
DOI/URL:
Notes: Article -- Source: Scopus
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  1. Stephen Solomon
    422 Solomon
  2. Etay   Ziv
    111 Ziv
  3. Amgad Mohamed Abdelhady Moussa
    34 Moussa