Authors: | Zakian, K. L.; Shukla-Dave, A.; Ackerstaff, E.; Hricak, H.; Koutcher, J. A. |
Article Title: | 1H magnetic resonance spectroscopy of prostate cancer: Biomarkers for tumor characterization |
Abstract: | Proton Magnetic Resonance Spectroscopic Imaging (MRSI) permits a non-invasive assessment of metabolites in the prostate gland. This article reviews the assessment of choline-containing compounds, citrate, and polyamines as markers for prostate tumor detection and aggressiveness. © 2008 IOS Press. All rights reserved. |
Keywords: | histopathology; review; cancer growth; cancer risk; cancer radiotherapy; nuclear magnetic resonance imaging; outcome assessment; methodology; cancer grading; diagnostic accuracy; sensitivity and specificity; cell proliferation; tumor markers, biological; signal noise ratio; in vivo study; in vitro study; pathology; tumor marker; risk assessment; prostate cancer; gleason score; prostatic neoplasms; standardization; diagnostic value; prostatectomy; image quality; three dimensional imaging; cancer cell; prostate tumor; prostate biopsy; magnetic resonance; magnetic resonance spectroscopy; choline; citric acid; nuclear magnetic resonance spectroscopy; prostate hypertrophy; detection; cell density; cancer classification; image processing; cell metabolism; spectroscopy; non invasive measurement; image display; patient care planning; roc curve; proton nuclear magnetic resonance; proton; tissue characterization; disease activity; polyamine; polyamine derivative; choline derivative; qualitative diagnosis; quantitative diagnosis; citrates; polyamines |
Journal Title: | Cancer Biomarkers |
Volume: | 4 |
Issue: | 4-5 |
ISSN: | 1574-0153 |
Publisher: | IOS Press |
Date Published: | 2008-01-01 |
Start Page: | 263 |
End Page: | 276 |
Language: | English |
PUBMED: | 18957715 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | --- - "Cited By (since 1996): 4" - "Export Date: 17 November 2011" - "Source: Scopus" |