Evidence-based botanical research: Applications and challenges Journal Article
| Authors: | Yeung, K. S.; Gubili, J.; Cassileth, B. |
| Article Title: | Evidence-based botanical research: Applications and challenges |
| Abstract: | Use of herbal supplements is on the rise around the world, but limited data exist on the safety and efficacy of botanical products. Efforts to subject botanicals to rigorous scientific research began recently. There are many problems associated with botanicals research, however. These include procuring the study agents, selecting appropriate study method and clinical trial design, navigating through regulatory obstacles, and obtaining funding. Evidence-based botanical research can help to validate traditional uses and to facilitate new drug development. Concerted efforts of governmental agencies and industry are essential to ensure continuance of high-quality botanicals research. © 2008 Elsevier Inc. All rights reserved. |
| Keywords: | cancer chemotherapy; clinical trial; review; placebo; drug efficacy; drug safety; nonhuman; unspecified side effect; clinical trials as topic; evidence based medicine; neoplasm; evidence-based medicine; neoplasms; quality control; animals; antineoplastic activity; drug screening; drug screening assays, antitumor; drug research; drug mechanism; alternative medicine; phytotherapy; plant preparations; herbaceous agent; clinical effectiveness; traditional medicine; drugs, investigational; green tea extract; herbal medicine; drug manufacture; drug identification; silybum marianum extract; hypericum perforatum extract; viscum album extract; nutritional value; catharanthus roseus extract; cimicifuga racemosa extract; taxus brevifolia extract; ethnobotany |
| Journal Title: | Hematology/Oncology Clinics of North America |
| Volume: | 22 |
| Issue: | 4 |
| ISSN: | 0889-8588 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2008-08-01 |
| Start Page: | 661 |
| End Page: | 670 |
| Language: | English |
| DOI: | 10.1016/j.hoc.2008.04.007 |
| PUBMED: | 18638694 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 6" - "Export Date: 17 November 2011" - "CODEN: HCNAE" - "Source: Scopus" |
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