Simultaneous occurrence of infantile hemangioma and congenital melanocytic nevus: Coincidence or real association? Journal Article


Authors: Wu, P. A.; Mancini, A. J.; Marghoob, A. A.; Frieden, I. J.
Article Title: Simultaneous occurrence of infantile hemangioma and congenital melanocytic nevus: Coincidence or real association?
Abstract: Both infantile hemangiomas (IH) and congenital melanocytic nevi (CMN) are common birthmarks that affect approximately 4% to 5% of infants and 1% of newborns, respectively. No previous association has been established between these birthmarks. We report a series of 6 patients who were remarkable for either the proximity or extent of anatomic involvement of their IH and CMN. Patient 1 had a large CMN in the area of her left eye and upper face in addition to a parotid IH. Likewise, patient 5 had a giant CMN on her back and a beard distribution IH. Patients 2, 3, and 4 were found to have small CMNs and localized IH in close anatomic proximity. Patient 6 was seen for a large left parietal scalp CMN with satellite nevi and multiple cutaneous hemangiomas. Although IH and CMN are common birthmarks, the clinical characteristics in these cases suggest a real, not coincidental association. Possible pathogenetic mechanisms to explain this association are discussed. © 2008 American Academy of Dermatology, Inc.
Keywords: adolescent; clinical article; preschool child; child, preschool; prednisolone; melanocytic nevus; infant; infant, newborn; nevus, pigmented; skin examination; physical examination; chromosome analysis; karyotyping; hemangioma; magnetic resonance angiography; laser therapy; pulsed dye laser; becaplermin; xipamide; skin hemangioma
Journal Title: Journal of the American Academy of Dermatology
Volume: 58
Issue: 2 SUPPL. 1
ISSN: 0190-9622
Publisher: Mosby Elsevier  
Date Published: 2008-02-01
Start Page: S16
End Page: S22
Language: English
DOI: 10.1016/j.jaad.2006.04.085
PUBMED: 18191691
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 3" - "Export Date: 17 November 2011" - "CODEN: JAADD" - "Source: Scopus"
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  1. Ashfaq A Marghoob
    534 Marghoob