Selection of unrelated donors and cord blood units for hematopoietic cell transplantation: Guidelines from the NMDP/CIBMTR Guidelines
| Authors: | Dehn, J.; Spellman, S.; Hurley, C. K.; Shaw, B. E.; Barker, J. N.; Burns, L. J.; Confer, D. L.; Eapen, M.; Fernandez-Vina, M.; Hartzman, R.; Maiers, M.; Marino, S. R.; Mueller, C.; Perales, M. A.; Rajalingam, R.; Pidala, J. |
| Title: | Selection of unrelated donors and cord blood units for hematopoietic cell transplantation: Guidelines from the NMDP/CIBMTR |
| Abstract: | Allogeneic hematopoietic cell transplantation involves consideration of both donor and recipient characteristics to guide the selection of a suitable graft. Sufficient high-resolution donor-recipient HLA match is of primary importance in transplantation with adult unrelated donors, using conventional graft-versus-host disease prophylaxis. In cord blood transplantation, optimal unit selection requires consideration of unit quality, cell dose and HLA-match. In this summary, the National Marrow Donor Program (NMDP) and the Center for International Blood and Marrow Transplant Research, jointly with the NMDP Histocompatibility Advisory Group, provide evidence-based guidelines for optimal selection of unrelated donors and cord blood units. |
| Keywords: | graft failure; versus-host-disease; class-i; high-risk; peripheral-blood; bone-marrow-transplantation; mismatches; anti-hla antibodies; amino-acid substitutions; natural-killer-cell; determines nonpermissive |
| Journal Title: | Blood |
| Volume: | 134 |
| Issue: | 12 |
| ISSN: | 0006-4971 |
| Publisher: | American Society of Hematology |
| Date Published: | 2019-09-19 |
| Start Page: | 924 |
| End Page: | 934 |
| Language: | English |
| ACCESSION: | WOS:000486618100003 |
| DOI: | 10.1182/blood.2019001212 |
| PROVIDER: | wos |
| PMCID: | PMC6753623 |
| PUBMED: | 31292117 |
| Notes: | Article -- Source: Wos |
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