Selection of unrelated donors and cord blood units for hematopoietic cell transplantation: Guidelines from the NMDP/CIBMTR Journal Article


Authors: Dehn, J.; Spellman, S.; Hurley, C. K.; Shaw, B. E.; Barker, J. N.; Burns, L. J.; Confer, D. L.; Eapen, M.; Fernandez-Vina, M.; Hartzman, R.; Maiers, M.; Marino, S. R.; Mueller, C.; Perales, M. A.; Rajalingam, R.; Pidala, J.
Article Title: Selection of unrelated donors and cord blood units for hematopoietic cell transplantation: Guidelines from the NMDP/CIBMTR
Abstract: Allogeneic hematopoietic cell transplantation involves consideration of both donor and recipient characteristics to guide the selection of a suitable graft. Sufficient high-resolution donor-recipient HLA match is of primary importance in transplantation with adult unrelated donors, using conventional graft-versus-host disease prophylaxis. In cord blood transplantation, optimal unit selection requires consideration of unit quality, cell dose and HLA-match. In this summary, the National Marrow Donor Program (NMDP) and the Center for International Blood and Marrow Transplant Research, jointly with the NMDP Histocompatibility Advisory Group, provide evidence-based guidelines for optimal selection of unrelated donors and cord blood units.
Keywords: graft failure; versus-host-disease; class-i; high-risk; peripheral-blood; bone-marrow-transplantation; mismatches; anti-hla antibodies; amino-acid substitutions; natural-killer-cell; determines nonpermissive
Journal Title: Blood
Volume: 132
Issue: 12
ISSN: 0006-4971
Publisher: American Society of Hematology  
Date Published: 2019-09-19
Start Page: 924
End Page: 934
Language: English
ACCESSION: WOS:000486618100003
DOI: 10.1182/blood.2019001212
PROVIDER: wos
PMCID: PMC6753623
PUBMED: 31292117
Notes: Article -- Source: Wos
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MSK Authors
  1. Miguel-Angel Perales
    397 Perales
  2. Juliet N Barker
    232 Barker