Development of a nursing policy for the administration of an oncolytic virus in the outpatient setting Review


Authors: Hom, V.; Karonis, E.; Sigidi, T.; Cawley, K.
Review Title: Development of a nursing policy for the administration of an oncolytic virus in the outpatient setting
Abstract: Objective: To describe the development of a nursing policy for the administration of oncolytic viruses in therapeutic clinical trials and the unique challenges for infection control and nursing. Data Source: Journal articles, web-based resources, peer-reviewed literature. Conclusion: Early nursing involvement and inclusion of multidisciplinary hospital departments facilitated the creation of a nursing policy that maintained fidelity to the research protocol and minimized potential risk to nursing staff. A total of 18 doses of oncolytic viruses were administered with no inadvertent exposures to staff or other patients of the oncolytic virus. Implications for Nursing Practice: Nursing should be involved at the initiation of a clinical trial to determine whether policies need to be created or changed to maintain the integrity of the research protocol while ensuring the safety of staff and patients. © 2019 Elsevier Inc.
Keywords: clinical trial; oncologic nursing; immunotherapy; oncolytic viruses; oncolytic virotherapy
Journal Title: Seminars in Oncology Nursing
Volume: 35
Issue: 5
ISSN: 0749-2081
Publisher: Elsevier Inc.  
Date Published: 2019-10-01
Start Page: 150928
Language: English
DOI: 10.1016/j.soncn.2019.08.007
PUBMED: 31514993
PROVIDER: scopus
DOI/URL:
Notes: Source: Scopus
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  1. Kristin Cawley
    5 Cawley
  2. Tara Denise Sigidi
    2 Sigidi
  3. Vania Hom
    3 Hom