Cobimetinib-induced “dropped head syndrome” and subsequent disease management in an Erdheim-Chester patient Journal Article
| Authors: | King, A. C.; Diamond, E. L.; Orozco, J. S.; Morse, H. R.; Ouyang, L. L.; Schöder, H.; Rampal, R. K. |
| Article Title: | Cobimetinib-induced “dropped head syndrome” and subsequent disease management in an Erdheim-Chester patient |
| Abstract: | Our rechallenge of cobimetinib in an Erdheim-Chester Disease (ECD) patient for the rare adverse effect, “dropped head syndrome,” with a previously unexplored cobimetinib regimen was successful. Similar to other experiences with targeted agents in ECD, dosing of cobimetinib may vary to mitigate toxicity without impairing efficacy. © 2019 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. |
| Keywords: | neurology; pharmacology; hematology; erdheim-chester disease |
| Journal Title: | Clinical Case Reports |
| Volume: | 7 |
| Issue: | 10 |
| ISSN: | 2050-0904 |
| Publisher: | Wiley Blackwell |
| Date Published: | 2019-10-01 |
| Start Page: | 1989 |
| End Page: | 1993 |
| Language: | English |
| DOI: | 10.1002/ccr3.2297 |
| PROVIDER: | scopus |
| PMCID: | PMC6787838 |
| PUBMED: | 31624624 |
| DOI/URL: | |
| Notes: | Article -- Export Date: 1 November 2019 -- Source: Scopus |
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