An evidence-based analysis of the management of N0 neck in patients with cancer of the parotid gland Review


Authors: Vartanian, J. G.; Gonçalves Filho, J.; Kowalski, L. P.; Shah, J. P.; Suárez, C.; Rinaldo, A.; De Bree, R.; Rodrigo, J. P.; Hamoir, M.; Takes, R. P.; Mäkitie, A. A.; Zbären, P.; Andreasen, S.; Poorten, V. V.; Sanabria, A.; Hellquist, H.; Robbins, K. T.; Bödeker, C. C.; Silver, C.; Ferlito, A.
Review Title: An evidence-based analysis of the management of N0 neck in patients with cancer of the parotid gland
Abstract: Introduction: Management of clinically negative neck (cN0) in patients with parotid gland cancer is controversial. Treatment options can include observation, elective neck dissection or elective radiotherapy. Areas covered: We addressed the treatment options for cN0 patients with parotid gland cancer. A literature review was undertaken to determine the optimal management of this group of patients. Expert opinion: Patients with parotid carcinoma and clinically negative neck have various options for their management. The analysis of tumor stage, histology and grade is essential to better define patients at risk for occult lymph node metastasis. These patients can be managed by surgery, radiotherapy or their combination, depending on the presence of risk factors, the moment at which such risk factors are detected, patient-related clinical conditions, medical provider expertise and institutional facilities. © 2019, © 2019 Informa UK Limited, trading as Taylor & Francis Group.
Keywords: cancer surgery; histopathology; review; neck dissection; treatment planning; cancer radiotherapy; cancer staging; lymph node metastasis; diagnostic accuracy; sentinel lymph node biopsy; tumor volume; radiotherapy; evidence based practice; risk factor; patient care; salivary gland; parotid gland; parotid gland carcinoma; neck metastasis; human; elective neck treatment; patient risk
Journal Title: Expert Review of Anticancer Therapy
Volume: 19
Issue: 10
ISSN: 1473-7140
Publisher: Taylor & Francis Group  
Date Published: 2019-01-01
Start Page: 899
End Page: 908
Language: English
DOI: 10.1080/14737140.2019.1674143
PUBMED: 31591950
PROVIDER: scopus
DOI/URL:
Notes: Source: Scopus
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  1. Jatin P Shah
    721 Shah