Consensus criteria for diagnosis, staging, and treatment response assessment of T-cell prolymphocytic leukemia Journal Article


Authors: Staber, P. B.; Herling, M.; Bellido, M.; Jacobsen, E. D.; Davids, M. S.; Kadia, T. M.; Shustov, A.; Tournilhac, O.; Bachy, E.; Zaja, F.; Porkka, K.; Hoermann, G.; Simonitsch-Klupp, I.; Haferlach, C.; Kubicek, S.; Mayerhoefer, M. E.; Hopfinger, G.; Jaeger, U.; Dearden, C.
Article Title: Consensus criteria for diagnosis, staging, and treatment response assessment of T-cell prolymphocytic leukemia
Abstract: T-cell prolymphocytic leukemia (T-PLL) is a rare, mature T-cell neoplasm with a heterogeneous clinical course. With the advent of novel treatment options that will potentially change the management of patients with T-PLL, it has become necessary to produce consensus guidelines for the design and conduct of clinical trials. The T-PLL International Study group (TPLL-ISG) set out to define standardized criteria for diagnosis, treatment indication, and evaluation of response. These criteria will facilitate comparison of results from clinical trials in T-PLL, and will thus support clinical decision making, as well as the approval of new therapeutics by healthcare authorities. © 2019 American Society of Hematology. All rights reserved.
Journal Title: Blood
Volume: 134
Issue: 14
ISSN: 0006-4971
Publisher: American Society of Hematology  
Date Published: 2019-10-03
Start Page: 1132
End Page: 1143
Language: English
DOI: 10.1182/blood.2019000402
PUBMED: 31292114
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 1 November 2019 -- Source: Scopus
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