Salt losing nephropathy simulating congenital adrenal hyperplasia in infants with obstructive uropathy and/or vesicoureteral reflux-value of ultrasonography in diagnosis Journal Article

  


Authors: Levin, T. L.; Abramson, S. J.; Burbige, K. A.; Connor, J. P.; Ruzal-Shapiro, C.; Berdon, W. E.
Article Title: Salt losing nephropathy simulating congenital adrenal hyperplasia in infants with obstructive uropathy and/or vesicoureteral reflux-value of ultrasonography in diagnosis
Abstract: Salt losing nephropathy, occurring predominantly in male infants, has been reported in association with a spectrum of urologic diseases including obstructive uropathy and massive, infected vesicoureteral reflux (VUR). This has been called pseudo-hypoaldosteronism (PHA) or alternatively, pseudo salt-losing congenital adrenal hyperplasia (CAH), and is thought to reflect a tubular unresponsiveness to aldosterone. We report our experience with six cases, discuss one case in detail and review the 39 cases previously reported. A one month old male infant presented with a left upper quadrant mass. Signs and symptoms included vomiting, dehydration, hyponatremia and hyperkalemia. This suggested the diagnosis of CAH for which therapy was instituted. Ultrasonographic examination subsequently revealed the mass to be a urinoma in an infant with posterior urethral valve (PUV) and obstructive hydronephrosis. © 1991 Springer-Verlag.
Keywords: clinical article; case report; diagnosis, differential; differential diagnosis; symptom; kidney; infant; infant, newborn; diagnosis; echography; newborn; urethra; hydronephrosis; prenatal diagnosis; fetus monitoring; vesicoureteral reflux; salt losing nephritis; obstructive uropathy; human; male; female; priority journal; article; child urology; congenital adrenal hyperplasia; adrenal hyperplasia, congenital; pseudohypoaldosteronism; urethral obstruction; vesico-ureteral reflux
Journal Title: Pediatric Radiology
Volume: 21
Issue: 6
ISSN: 0301-0449
Publisher: Springer  
Date Published: 1991-10-01
Start Page: 413
End Page: 415
Language: English
DOI: 10.1007/bf02026675
PUBMED: 1749673
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-0025951150&doi=10.1007%2fBF02026675&partnerID=40&md5=04cd803615bc06f44d56700d1bfbca98
Notes: Source: Scopus
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