Author: | Posner, J. B. |
Article Title: | Paraneoplastic syndromes |
Abstract: | Paraneoplastic syndromes affects the nervous system in a very small percentage of patients with cancer. In those patients, portions of the nervous system are damaged or destroyed, usually in association with a small and often occult neoplasm elsewhere in the body. Current evidence suggests that these syndromes occur when the body mounts an immune response to an antigen shared between the tumor and the nervous system. The immune attack is then misdirected against that portion of the nervous system that possesses the ''onconeural'' antigen. |
Keywords: | human tissue; fluorouracil; cytarabine; diagnosis, differential; neuropathy; dermatomyositis; corticosteroid; eaton lambert syndrome; opsoclonus; paraneoplastic syndrome; neurologic examination; corticotropin; nervous system diseases; paraneoplastic syndromes; polymyositis; cerebellum degeneration; human; male; female; article; retina degeneration |
Journal Title: | Neurologic Clinics |
Volume: | 9 |
Issue: | 4 |
ISSN: | 0733-8619 |
Publisher: | W.B. Saunders Co-Elsevier Inc. |
Date Published: | 1991-11-01 |
Start Page: | 919 |
End Page: | 936 |
Language: | English |
PUBMED: | 1758432 |
PROVIDER: | scopus |
DOI: | 10.1016/S0733-8619(18)30257-3 |
DOI/URL: | |
Notes: | Source: Scopus |