In vivo measurements of bone marrow cellularity using volume‐localized proton NMR spectroscopy Journal Article
| Authors: | Ballon, D.; Jakubowski, A.; Gabrilove, J.; Graham, M. C.; Zakowski, M.; Sheridan, C.; Koutcher, J. A. |
| Article Title: | In vivo measurements of bone marrow cellularity using volume‐localized proton NMR spectroscopy |
| Abstract: | Volume‐localized proton NMR spectroscopy was used to estimate bone marrow cellularity in the posterior iliac crests of patients undergoing treatment with hematopoietic growth factors for a variety of hematologic and neoplastic disorders. Twelve patients were accrued, six of whom were studied more than once, yielding a total of 25 measurements. These data were compared to cellularity assessments derived from conventional bone marrow core biopsies obtained within a 24‐h period before or after the NMR exam. The results obtained by the two methods are well correlated (R = 0.94, P < 0.001), suggesting that this noninvasive technique may preclude the need for biopsies in some cases. © 1991 Academic Press, Inc. Copyright © 1991 Wiley‐Liss, Inc., A Wiley Company |
| Keywords: | adult; clinical article; aged; neutropenia; magnetic resonance imaging; neoplasms; bone marrow; biopsy; diagnosis; magnetic resonance spectroscopy; hematopoiesis; nuclear magnetic resonance; hematologic diseases; middle age; ilium; cancer; human; male; female; article; support, non-u.s. gov't; support, u.s. gov't, p.h.s.; hematopoietic cell growth factors |
| Journal Title: | Magnetic Resonance in Medicine |
| Volume: | 19 |
| Issue: | 1 |
| ISSN: | 0740-3194 |
| Publisher: | John Wiley & Sons |
| Date Published: | 1991-05-01 |
| Start Page: | 85 |
| End Page: | 95 |
| Language: | English |
| DOI: | 10.1002/mrm.1910190108 |
| PUBMED: | 2046540 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Source: Scopus |
Altmetric
Citation Impact
BMJ Impact Analytics
Related MSK Work