Three-dimensional treatment planning for postoperative treatment of rectal carcinoma Journal Article


Authors: Shank, B.; Losasso, T.; Brewster, L.; Burman, C.; Cheng, E.; Chu, J. C. H.; Drzymala, R. E.; Manolis, J.; Pilepich, M. V.; Solin, L. J.; Tepper, J. E.; Urie, M. M.
Article Title: Three-dimensional treatment planning for postoperative treatment of rectal carcinoma
Abstract: The role of three-dimensional (3-D) treatment planning for postoperative radiation therapy was evaluated for rectal carcinoma as part of an NCI contract awarded to four institutions. It was found that the most important contribution of 3-D planning for this site was the ability to plan and localize target and normal tissues at all levels of the treatment volume, rather than using the traditional method of planning with only a single central transverse slice and simulation films. There was also a slight additional improvement when there were no constraints on the types of plans (i.e., when noncoplanar beams were used). Inhomogeneity considerations were not important at this site under the conditions of planning, i.e., with energies >4 MV and multiple fields. Higher beam energies (15-25 MV) were preferred by a small margin over lower energies (down to 4 MV). The beam's eye view and dose-volume histograms were found quite useful as planning tools, but it was clear that work should continue on better 3-D displays and improved means of translating such plans to the treatment area. © 1991.
Keywords: adult; controlled study; cancer surgery; case report; cancer radiotherapy; postoperative care; combined modality therapy; radiotherapy dosage; three dimensional imaging; radiotherapy planning, computer-assisted; rectum carcinoma; rectal neoplasms; histogram; middle age; rectal carcinoma; dose-volume histograms; three-dimensional treatment planning; human; male; female; priority journal; article; support, u.s. gov't, p.h.s.; x ray dose distribution; beam's eye view
Journal Title: International Journal of Radiation Oncology, Biology, Physics
Volume: 21
Issue: 1
ISSN: 0360-3016
Publisher: Elsevier Inc.  
Date Published: 1991-05-15
Start Page: 253
End Page: 265
Language: English
DOI: 10.1016/0360-3016(91)90183-5
PUBMED: 2032894
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 27 September 2019 -- Source: Scopus
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MSK Authors
  1. Chandra M Burman
    154 Burman
  2. Thomas J LoSasso
    99 LoSasso
  3. Brenda M. Shank
    45 Shank
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