Histogram reduction method for calculating complication probabilities for three-dimensional treatment planning evaluations Journal Article

  


Authors: Kutcher, G. J.; Burman, C.; Brewster, L.; Goitein, M.; Mohan, R.
Article Title: Histogram reduction method for calculating complication probabilities for three-dimensional treatment planning evaluations
Abstract: New tools are needed to help in evaluating 3-D treatment plans because of the large volume of data. One technique which may prove useful is the application of complication probability calculations. A method of calculating complication probabilities for inhomogeneously irradiated normal tissues is presented in this paper. The method uses clinical estimates of tolerance doses for a few discreet conditions of uniform partial organ irradiation, an empirical fit of a continuous function to these data, and a technique (the effective volume method) for transforming nonuniform dose-volume histograms into equivalent uniform histograms. The behavior of the effective volume histogram reduction method for various boundary conditions is reviewed. The use of complication probabilities in evaluating treatment plans is presented, using examples from an NCI 3-D treatment planning contract. © 1991.
Keywords: controlled study; cancer radiotherapy; neoplasms; radiotherapy dosage; radiotherapy; probability; radiotherapy planning, computer-assisted; histogram; complication; scoring; human; priority journal; article; support, u.s. gov't, p.h.s.; multidirectional tomography; 3-d treatment planning; complication probability calculations; treatment planning evaluation
Journal Title: International Journal of Radiation Oncology, Biology, Physics
Volume: 21
Issue: 1
ISSN: 0360-3016
Publisher: Elsevier Inc.  
Date Published: 1991-05-15
Start Page: 137
End Page: 146
Language: English
DOI: 10.1016/0360-3016(91)90173-2
PUBMED: 2032884
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-0026093854&doi=10.1016%2f0360-3016%2891%2990173-2&partnerID=40&md5=02adce7e3a5b1338224a14bd9f5b6094
Notes: Article -- Export Date: 27 September 2019 -- Source: Scopus
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MSK Authors
  1. Chandra M Burman
    154 Burman
  2. Gerald J Kutcher
    106 Kutcher
  3. Radhe Mohan
    97 Mohan
  4. Linda J. Brewster
    20 Brewster Mallalieu
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