Interinstitutional experience in verification of external photon dose calculations Journal Article


Authors: Masterson, M. E.; Barest, G.; Chui, C. S.; Doppke, K. P.; Epperson, R. D.; Harms, W. B.; Krippner, K. E.; Mohan, R.; Slessinger, E. D.; Sontag, M. R.; Urie, M. M.; Wallace, R. E.; Wong, J. W.
Article Title: Interinstitutional experience in verification of external photon dose calculations
Abstract: Under the auspices of NCI contracts, four institutions have collaborated to assess the accuracy of the pixel-based dose calculation methods they employ for external photon treatment planning. The approach relied on comparing calculations using each group's algorithm with measurements in phantoms of increasing complexity. The first set of measurements consisted of ionization chamber measurements in water phantoms in normally incident square fields, an elongated field, a wedged field, a blocked field, and an obliquely incident beam. The second group of measurements was carried out using thermoluminescent dosimeters in phantoms designed to investigate the effects of surface curvature, high density heterogeneities, and low density heterogeneities. The final study tested the entire treatment planning system, including CT data conversion, in an anthropomorphic phantom. Overall, good agreement between calculation and measurements was found for all algorithms. Regions in which discrepancies were observed are pointed out, areas for algorithm improvement are identified and the clinical import of algorithm accuracy is discussed. © 1991.
Keywords: controlled study; treatment planning; cancer radiotherapy; neoplasms; computer assisted tomography; radiotherapy dosage; algorithm; dosimetry; radiotherapy planning, computer-assisted; phantom; scattering, radiation; dose calculations; human; priority journal; article; support, u.s. gov't, p.h.s.; algorithm accuracy; external photon treatment planning
Journal Title: International Journal of Radiation Oncology, Biology, Physics
Volume: 21
Issue: 1
ISSN: 0360-3016
Publisher: Elsevier Inc.  
Date Published: 1991-05-15
Start Page: 37
End Page: 58
Language: English
DOI: 10.1016/0360-3016(91)90166-2
PUBMED: 2032896
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 27 September 2019 -- Source: Scopus
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  1. Chen Chui
    144 Chui
  2. Radhe   Mohan
    97 Mohan