Mucolytic-antifoam solution for reduction of artifacts during endoscopic ultrasonography: A randomized controlled trial Journal Article
| Authors: | Yiengpruksawan, A.; Lightdale, C. J.; Gerdes, H.; Botet, J. F. |
| Article Title: | Mucolytic-antifoam solution for reduction of artifacts during endoscopic ultrasonography: A randomized controlled trial |
| Abstract: | Gastric mucus and air bubbles are frequent sources of artifacts during endoscopic ultrasonography (EUS). To reduce these artifacts, we prepared a mucolytic-antifoam solution consisting of simethicone, acetyicysteine, and sodium bicarbonate and performed a prospective randomized and controlled trial comparing this solution (21 patients) to a placebo (22 patients) during EUS. Eight patients in the drug group received a perfect score for both mucolytic and antifoam effect compared with none in the placebo group (p < 0.001). For overall rating, the drug group received a total of 10 excellents and 9 goods compared with 9 goods, 10 satisfactories, and 1 unacceptable in the placebo group (p < 0.001). There were no complications associated with the solution. In conclusion, a mucolytic-antifoam solution improved endoscopic visualization and reduced artifacts during EUS study. Its routine use during EUS procedures is therefore recommended. © 1991, American Society for Gastrointestinal Endoscopy. All rights reserved. |
| Keywords: | adult; clinical article; controlled study; aged; placebo; image quality; diagnosis; echography; gastroscopy; stomach; oral drug administration; bicarbonate; acetylcysteine; simethicone; human; male; female; priority journal; article; mucolysis |
| Journal Title: | Gastrointestinal Endoscopy |
| Volume: | 37 |
| Issue: | 5 |
| ISSN: | 0016-5107 |
| Publisher: | Mosby Elsevier |
| Date Published: | 1991-09-01 |
| Start Page: | 543 |
| End Page: | 546 |
| Language: | English |
| DOI: | 10.1016/s0016-5107(91)70825-0 |
| PUBMED: | 1657680 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Source: Scopus |
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