Conservative management of anal leiomyosarcoma Journal Article


Authors: Minsky, B. D.; Cohen, A. M.; Hajdu, S. I.
Article Title: Conservative management of anal leiomyosarcoma
Abstract: Leiomyosarcomas of the large intestine are unusual neoplasms, comprising less than 0.1% of all malignancies of the colon and rectum. Six cases of leiomyosarcoma of the anus have been reported. The optimal treatment for this neoplasm is not known. The standard surgical approach is abdominoperineal resection. The authors report the seventh case of this rare neoplasm and outline its treatment using local excision and iridium 192 brachytherapy in an attempt to preserve the anal sphincter. In selected patients, conservative surgery followed by radiation therapy may be an alternative to radical surgery, with the goals of local control of the disease and anal sphincter preservation. However, more experience is needed before this approach could be recommended routinely. Copyright © 1991 American Cancer Society
Keywords: adult; human tissue; case report; combined modality therapy; radiotherapy dosage; histology; brachytherapy; leiomyosarcoma; anus cancer; iridium 192; iridium radioisotopes; middle age; anus neoplasms; human; female; priority journal; article; support, non-u.s. gov't
Journal Title: Cancer
Volume: 68
Issue: 7
ISSN: 0008-543X
Publisher: Wiley Blackwell  
Date Published: 1991-10-01
Start Page: 1640
End Page: 1643
Language: English
DOI: 10.1002/1097-0142(19911001)68:7<1640::Aid-cncr2820680729>3.0.Co;2-6
PUBMED: 1893364
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 27 September 2019 -- Source: Scopus
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MSK Authors
  1. Bruce Minsky
    306 Minsky
  2. Alfred M Cohen
    244 Cohen
  3. Steven I. Hajdu
    80 Hajdu
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