Early gastric cancer: Twenty-eight-year experience Journal Article


Authors: Lawrence, M.; Shiu, M. H.
Article Title: Early gastric cancer: Twenty-eight-year experience
Abstract: A retrospective study of early gastric cancer (60 patients) was performed to evaluate its diagnosis and treatment. Ninety-five per cent of patients presented with nonspecific gastrointestinal symptoms and 53.3% had been treated for presumed benign disease for up to 48 months before diagnosis. Fiberoptic endoscopy detected these lesions more accurately than radiologic examination. The disease-free 5-year survival rate after resection was 76.4%. Survival showed no significant correlation with sex, tumor site, macroscopic appearance, extent of gastric resection, or histopathologic type. Tumors larger than 1.5 cm in diameter, invasion of submucosa, or lymph node metastasis resulted in significantly lower survival rates. Three of eight patients with nodal metastasis survived 5 or more years, including one who had second-echelon deposits. A high index of suspicion may permit more frequent detection. Extended lymphadenectomy (R2) is recommended to achieve the highest possible cure rate.
Keywords: adult; aged; aged, 80 and over; survival rate; retrospective studies; major clinical study; combined modality therapy; lymph node metastasis; lymph node dissection; lymphatic metastasis; lymph node excision; prospective studies; adenocarcinoma; pain; time factors; early cancer; neoplasm metastasis; new york city; stomach cancer; dyspepsia; stomach neoplasms; gastroscopy; middle age; human; male; female; priority journal; article
Journal Title: Annals of Surgery
Volume: 213
Issue: 4
ISSN: 0003-4932
Publisher: Lippincott Williams & Wilkins  
Date Published: 1991-04-01
Start Page: 327
End Page: 334
Language: English
DOI: 10.1097/00000658-199104000-00007
PUBMED: 2009014
PROVIDER: scopus
PMCID: PMC1358351
DOI/URL:
Notes: Article -- Export Date: 27 September 2019 -- Source: Scopus
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  1. Man-Hei Shiu
    44 Shiu