Invasive thyroid cancer: Management of the trachea and esophagus Journal Article

   


Authors: Price, D. L.; Wong, R. J.; Randolph, G. W.
Article Title: Invasive thyroid cancer: Management of the trachea and esophagus
Abstract: Well-differentiated thyroid cancer most commonly presents as an intrathyroidal tumor; however, extrathyroidal extension occurs in approximately 6% to 13% of patients and carries a significant negative impact on survival. Extrathyroidal disease may involve critical structures in the central neck, including the recurrent laryngeal nerves, trachea, esophagus, and larynx, requiring surgery extending significantly beyond the thyroid gland. Appropriate surgical management is of great importance and can normalize survival curves, whereas gross residual disease postoperatively may lead to recurrence and decreased survival. Adjuvant postoperative therapies for thyroid cancers with extrathyroidal extension include thyroid hormone suppression, radioactive iodine therapy, and external beam radiotherapy. This summary reviews approaches to the management of invasive thyroid cancers involving the aerodigestive tract. © 2008 Elsevier Inc. All rights reserved.
Keywords: cancer survival; clinical feature; review; doxorubicin; combined modality therapy; gadolinium; cancer staging; nuclear magnetic resonance imaging; computer assisted tomography; cancer invasion; iodine 131; radioactive iodine; clinical evaluation; neoplasm invasiveness; thyroid cancer; thyroid neoplasms; external beam radiotherapy; suture techniques; vocal cord paralysis; larynx; tracheostomy; iodinated contrast medium; esophagus; retinoid; esophagus tumor; recurrent laryngeal nerve; trachea; topical anesthesia; cartilage; trachea tumor
Journal Title: Otolaryngologic Clinics of North America
Volume: 41
Issue: 6
ISSN: 0030-6665
Publisher: Elsevier Inc.  
Date Published: 2008-12-01
Start Page: 1155
End Page: 1168
Language: English
DOI: 10.1016/j.otc.2008.08.002
PUBMED: 19040976
PROVIDER: scopus
PMCID: PMC2750808
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-56749177057&partnerID=40&md5=f5eba88ea45a88a83371dd844b5d9796
Notes: --- - "Cited By (since 1996): 2" - "Export Date: 17 November 2011" - "CODEN: OCNAB" - "Source: Scopus"
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MSK Authors
  1. Daniel Louis Price
    6 Price
  2. Richard J Wong
    411 Wong
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