A preeclampsia-like syndrome characterized by reversible hypertension and proteinuria induced by the multitargeted kinase inhibitors sunitinib and sorafenib Journal Article
| Authors: | Patel, T. V.; Morgan, J. A.; Demetri, G. D.; George, S.; Maki, R. G.; Quigley, M.; Humphreys, B. D. |
| Article Title: | A preeclampsia-like syndrome characterized by reversible hypertension and proteinuria induced by the multitargeted kinase inhibitors sunitinib and sorafenib |
| Keywords: | signal transduction; unclassified drug; gene deletion; sorafenib; bevacizumab; sunitinib; drug dose reduction; drug efficacy; drug withdrawal; hypertension; nonhuman; solid tumor; antineoplastic agents; benzenesulfonates; pyridines; receptors, vascular endothelial growth factor; drug targeting; antineoplastic agent; letter; biological marker; metabolism; gastrointestinal stromal tumor; stem cell factor receptor; vasculotropin receptor; edema; nephrotoxicity; protein kinase inhibitor; antineoplastic activity; drug effect; platelet derived growth factor receptor; vasculotropin inhibitor; protein kinase inhibitors; hypoalbuminemia; drug mechanism; kidney function; gene disruption; chemically induced disorder; antiangiogenic therapy; glomerulonephritis; antihypertensive agent; indoles; pyrroles; protein urine level; indole derivative; proteinuria; thrombotic thrombocytopenic purpura; pyrrole derivative; benzenesulfonic acid derivative; pyridine derivative; hemangioendothelioma; preeclampsia; blood pressure monitoring; capillary endothelium; krn 951; podocyte; preeclampsia like syndrome; renovascular disease; teratocarcinoma |
| Journal Title: | JNCI: Journal of the National Cancer Institute |
| Volume: | 100 |
| Issue: | 4 |
| ISSN: | 0027-8874 |
| Publisher: | Oxford University Press |
| Date Published: | 2008-02-01 |
| Start Page: | 282 |
| End Page: | 284 |
| Language: | English |
| DOI: | 10.1093/jnci/djm311 |
| PUBMED: | 18270341 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 40" - "Export Date: 17 November 2011" - "CODEN: JNCIA" - "Source: Scopus" |
