Craniofacial resection for tumors involving the anterior skull base Conference Paper
| Authors: | Shah, J. P.; Kraus, D. H.; Arbit, E.; Galicich, J. H.; Strong, E. W. |
| Title: | Craniofacial resection for tumors involving the anterior skull base |
| Conference Title: | Annual Meeting of the American Academy of Otolaryngology - Head and Neck Surgery |
| Abstract: | A consecutive series of 71 patients who underwent craniofacial resection between 1974 and 1990 for tumors that involved the anterior cranial base was reviewed. A variety of histologic diagnoses was present in this series. The most prevalent sites of origin included the nasal cavity, ethmoid sinus, and frontal sinus. Gross tumor removal was achieved in all patients, with 29 requiring orbital exenteration. Adjuvant radiation therapy was used in 25 patients. Two patients died of postoperative complications and 26 had complications that increased morbidity and length of hospitalization. Five- year overall survival was 56%, with a median survival of 4.2 years. Local control was observed in 40 of 56 patients with negative margins and 9 of 15 patients with positive margins. There was no difference in survival between previously treated and untreated patients. Survival varied considerably among the various pathologic diagnoses. Survival was related to the extent of disease. Patients with either dural or brain invasion had significantly decreased survival compared to those with no dural invasion. The operative procedure is safe, with acceptable morbidity and mortality, and offers respectable survival in properly selected patients. |
| Keywords: | adolescent; adult; cancer survival; child; human tissue; aged; cancer surgery; surgical technique; major clinical study; cancer recurrence; conference paper; cancer radiotherapy; postoperative complication; cancer invasion; craniofacial surgery; skull base tumor; prognosis; human; male; female; priority journal |
| Journal Title | Otolaryngology - Head and Neck Surgery |
| Volume: | 106 |
| Issue: | 4 |
| Conference Dates: | 1991 Sep 22-26 |
| Conference Location: | Kansas City, MO |
| ISBN: | 0194-5998 |
| Publisher: | Sage Publications |
| Date Published: | 1992-04-01 |
| Start Page: | 387 |
| End Page: | 393 |
| Language: | English |
| DOI: | 10.1177/019459989210600412 |
| PUBMED: | 1565489 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Conference Paper -- Export Date: 30 July 2019 -- Source: Scopus |
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