Invasive pulmonary aspergillosis, part 1: Diagnosis Journal Article


Authors: Papanicolaou, G. A.; White, D. A.
Article Title: Invasive pulmonary aspergillosis, part 1: Diagnosis
Abstract: The diagnosis of invasive pulmonary aspergillosis remains challenging because of atypical clinical presentations, comorbid diseases, and the difficulty in culturing Aspergillus by standard microbiological techniques. Serial monitoring with CT scans of the chest and serological markers can help with early identification in high-risk patients, such as hematopoietic stem cell transplant recipients. The most common radiographic findings are single or multiple nodules, wedge-shaped pleural-based infiltrates, and cavities. The halo sign is the most suggestive clue to aspergillosis and is manifested by a macronodule surrounded by a perimeter of ground-glass opacity.
Keywords: computer assisted tomography; hematopoietic stem cell transplantation; transplantation; high risk patient; early diagnosis; serodiagnosis; aspergillus; aspergillosis; lung aspergillosis; graft recipient; hematological malignancy
Journal Title: Journal of Respiratory Diseases
Volume: 29
Issue: 10
ISSN: 0194-259X
Publisher: Cliggott  
Date Published: 2008-10-01
Start Page: 405
End Page: 410
Language: English
PROVIDER: scopus
DOI/URL:
Notes: --- - "Export Date: 17 November 2011" - "CODEN: JRDIF" - "Source: Scopus"