Coupling reactions of hindered isonitriles and hindered alkyl thioacids: mechanistic studies Journal Article
| Authors: | Stockdill, J. L.; Wu, X.; Danishefsky, S. J. |
| Article Title: | Coupling reactions of hindered isonitriles and hindered alkyl thioacids: mechanistic studies |
| Abstract: | The coupling reaction between hindered thioacids and isonitriles is developed and described. The mechanism for the formation of the thiopyruvamide products is explored, and the method is applied to a selection of substrates. © 2009 Elsevier Ltd. All rights reserved. |
| Keywords: | crystal structure; reaction analysis; isonitrile derivative; proton nuclear magnetic resonance; quantum yield; amide; thioacid; alkyl group; pyruvic acid derivative; biotransformation; carbon nuclear magnetic resonance; cross coupling reaction |
| Journal Title: | Tetrahedron Letters |
| Volume: | 50 |
| Issue: | 36 |
| ISSN: | 0040-4039 |
| Publisher: | Pergamon-Elsevier Science Ltd |
| Date Published: | 2009-09-09 |
| Start Page: | 5152 |
| End Page: | 5155 |
| Language: | English |
| DOI: | 10.1016/j.tetlet.2009.06.129 |
| PROVIDER: | scopus |
| PMCID: | PMC2758784 |
| PUBMED: | 20160954 |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 4" - "Export Date: 30 November 2010" - "CODEN: TELEA" - "Source: Scopus" |
