(3R,9R,10R)-Panaxytriol: a molecular-based nutraceutical with possible application to cancer prevention and treatment Journal Article
| Authors: | Ng, F.; Yun, H.; Lei, X.; Danishefsky, S. J.; Fahey, J.; Stephenson, K.; Flexner, C.; Lee, L. |
| Article Title: | (3R,9R,10R)-Panaxytriol: a molecular-based nutraceutical with possible application to cancer prevention and treatment |
| Abstract: | Panaxytriol is a nutraceutical-based active constituent of Korean red ginseng and is reported to exhibit potent anti-tumor properties. Its activity may be in part due to its induction of phase 2 chemoprotective enzymes. Its unique properties may have important implications in cancer therapeutics. © 2008 Elsevier Ltd. All rights reserved. |
| Keywords: | unclassified drug; nonhuman; animal cell; mouse; cancer prevention; antineoplastic activity; cytotoxicity; structure activity relation; drug mechanism; breast carcinoma; lymphoma; melanoma cell; detoxification; traditional medicine; natural product; stomach carcinoma; synthesis; enzyme induction; medicinal plant; korea; phytochemistry; panaxytriol; ginseng; reduced nicotinamide adenine dinucleotide (phosphate) dehydrogenase (quinone); ginseng extract; nutraceutical; protopanaxatriol; panax ginseng |
| Journal Title: | Tetrahedron Letters |
| Volume: | 49 |
| Issue: | 50 |
| ISSN: | 0040-4039 |
| Publisher: | Pergamon-Elsevier Science Ltd |
| Date Published: | 2008-12-08 |
| Start Page: | 7178 |
| End Page: | 7179 |
| Language: | English |
| DOI: | 10.1016/j.tetlet.2008.09.169 |
| PROVIDER: | scopus |
| PMCID: | PMC2598768 |
| PUBMED: | 20011028 |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 4" - "Export Date: 17 November 2011" - "CODEN: TELEA" - "Source: Scopus" |
