(3R,9R,10R)-Panaxytriol: a molecular-based nutraceutical with possible application to cancer prevention and treatment Journal Article


Authors: Ng, F.; Yun, H.; Lei, X.; Danishefsky, S. J.; Fahey, J.; Stephenson, K.; Flexner, C.; Lee, L.
Article Title: (3R,9R,10R)-Panaxytriol: a molecular-based nutraceutical with possible application to cancer prevention and treatment
Abstract: Panaxytriol is a nutraceutical-based active constituent of Korean red ginseng and is reported to exhibit potent anti-tumor properties. Its activity may be in part due to its induction of phase 2 chemoprotective enzymes. Its unique properties may have important implications in cancer therapeutics. © 2008 Elsevier Ltd. All rights reserved.
Keywords: unclassified drug; nonhuman; animal cell; mouse; cancer prevention; antineoplastic activity; cytotoxicity; structure activity relation; drug mechanism; breast carcinoma; lymphoma; melanoma cell; detoxification; traditional medicine; natural product; stomach carcinoma; synthesis; enzyme induction; medicinal plant; korea; phytochemistry; panaxytriol; ginseng; reduced nicotinamide adenine dinucleotide (phosphate) dehydrogenase (quinone); ginseng extract; nutraceutical; protopanaxatriol; panax ginseng
Journal Title: Tetrahedron Letters
Volume: 49
Issue: 50
ISSN: 0040-4039
Publisher: Pergamon-Elsevier Science Ltd  
Date Published: 2008-12-08
Start Page: 7178
End Page: 7179
Language: English
DOI: 10.1016/j.tetlet.2008.09.169
PROVIDER: scopus
PMCID: PMC2598768
PUBMED: 20011028
DOI/URL:
Notes: --- - "Cited By (since 1996): 4" - "Export Date: 17 November 2011" - "CODEN: TELEA" - "Source: Scopus"
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