Evaluating tisagenlecleucel and its potential in the treatment of relapsed or refractory diffuse large B cell lymphoma: Evidence to date Review


Authors: Zavras, P. D.; Wang, Y.; Gandhi, A.; Lontos, K.; Delgoffe, G. M.
Review Title: Evaluating tisagenlecleucel and its potential in the treatment of relapsed or refractory diffuse large B cell lymphoma: Evidence to date
Abstract: Chimeric antigen receptor (CAR) T cells have changed the treatment landscape of relapsed or refractory diffuse large B cell lymphoma. This review focuses on the biology of tisagenlecleucel and the clinical data that support its use in this setting. In addition, we discuss how it compares to other CAR T products, the financial implications for payers, and ongoing trials. © 2019 Zavras et al.
Keywords: lymphoma; dlbcl; diffuse large b cell lymphoma; tisagenlecleucel; car t; refractory dlbcl
Journal Title: OncoTargets and Therapy
Volume: 12
ISSN: 1178-6930
Publisher: Dove Medical Press Ltd  
Date Published: 2019-06-11
Start Page: 4543
End Page: 4554
Language: English
DOI: 10.2147/ott.S177844
PROVIDER: scopus
PMCID: PMC6572744
PUBMED: 31354288
DOI/URL:
Notes: Review -- Export Date: 2 August 2019 -- Source: Scopus
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  1. Faidon Zavras
    11 Zavras