Author: | Offit, K. |
Article Title: | Chromosome analysis in the management of patients with non-Hodgkin's lymphoma |
Abstract: | Analysis of chromosome abnormalities in non-Hodgkin's lymphoma has stimulated a basic inquiry into the mechanisms of gene deregulation in human tumors. A growing literature has also correlated cytogenetic and molecular genetic features of lymphoma with patient prognosis and other clinical features of the disease. The goal of this report is to review those genetic abnormalities which are currently useful in the clinical management of patients with lymphoma, and to provide a conceptual framework for this growing literature. © 1992 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted. |
Keywords: | clinical feature; review; molecular genetics; chromosome 1; cytogenetics; gene expression regulation; patient care; nonhodgkin lymphoma; non-hodgkin's lymphoma; lymphoma, non-hodgkin; chromosome aberrations; chromosome 8; chromosome analysis; karyotype; karyotyping; chromosome 18; chromosome 2; therapy; chromosome 17; reciprocal chromosome translocation; molecular diagnostics; numerical chromosome aberration; chromosome 14; prognosis; human; support, non-u.s. gov't; support, u.s. gov't, p.h.s.; chromosome translocations; translocation (genetics) |
Journal Title: | Leukemia and Lymphoma |
Volume: | 7 |
Issue: | 4 |
ISSN: | 1042-8194 |
Publisher: | Taylor & Francis Group |
Date Published: | 1992-07-01 |
Start Page: | 275 |
End Page: | 282 |
Language: | English |
DOI: | 10.3109/10428199209049778 |
PUBMED: | 1493426 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | Source: Scopus |