Bacillus Calmette-Guerin therapy for superficial bladder cancer: A 10-year followup Journal Article


Authors: Herr, H. W.; Wartinger, D. D.; Fair, W. R.; Oettgen, H. F.
Article Title: Bacillus Calmette-Guerin therapy for superficial bladder cancer: A 10-year followup
Abstract: We report the outcome of 61 patients with superficial bladder tumors who received bacillus Calmette-Guerin (BCG) therapy and were followed for at least 10 years (range 10 to 13 years). A total of 19 patients (31%) remains free of tumor and progression, 17 (28%) had interval superficial recurrences but no progression and 25 (41%) had progression, first identified as muscle invasion in 12, prostatic involvement in 8 or metastasis in 5. Most tumors recurred or progressed within the first 5 years. Of the 61 patients 33 (54%) are disease-free and with an intact bladder, 13 (21%) are alive after cystectomy, 2 (3%) died of other causes, 1 (2%) is alive with metastasis and 12 (20%) died of metastatic urothelial cancer (11 from the bladder or prostate and 1 from an upper tract tumor).
Keywords: adult; aged; middle aged; cancer staging; follow up; follow-up studies; neoplasm staging; bcg vaccine; metastasis; neoplasm recurrence, local; carcinoma, papillary; pathology; bladder tumor; urinary bladder neoplasms; time; time factors; cancer invasion; tumor recurrence; carcinoma in situ; neoplasm invasiveness; papillary carcinoma; multiple cancer; neoplasms, multiple primary; humans; human; male; female; article
Journal Title: Journal of Urology
Volume: 147
Issue: 4
ISSN: 0022-5347
Publisher: Elsevier Science, Inc.  
Date Published: 1992-04-01
Start Page: 1020
End Page: 1023
Language: English
DOI: 10.1016/s0022-5347(17)37452-9
PUBMED: 1552578
PROVIDER: scopus
DOI/URL:
Notes: Source: Scopus
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  1. Harry W Herr
    595 Herr
  2. Herbert F Oettgen
    130 Oettgen
  3. William R Fair
    342 Fair