The use of the extended anterolateral thigh flap for reconstruction of massive oncologic defects Journal Article


Authors: Mosahebi, A.; Disa, J. J.; Pusic, A. L.; Cordeiro, P. G.; Mehrara, B. J.
Article Title: The use of the extended anterolateral thigh flap for reconstruction of massive oncologic defects
Abstract: BACKGROUND: Although the anterolateral thigh flap has been used extensively in reconstruction, the use of large or extended skin paddles (i.e., >240 cm) is thought to be associated with an increased risk of partial flap necrosis. This assumption may be attributable to cadaver perfusion studies of isolated anterolateral thigh flaps. The authors' clinical experience has shown, however, that significantly larger flaps can be reliably harvested based on the standard skin perforators. The purpose of this report was therefore to evaluate the authors' clinical experience with the extended anterolateral thigh flap for reconstruction of oncologic defects. METHODS: All consecutive patients who had undergone reconstruction of oncologic defects using an extended anterolateral thigh flap (defined as ≥240 cm) were identified. Patient characteristics and outcome data were analyzed. RESULTS: Fifteen patients met the inclusion criteria (flap size >240 cm) during the study period. The average size of the flaps was 341 cm (range, 240 to 480 cm). All flaps were perforator flaps and most had one perforator. In two patients, anterolateral thigh- and tensor fasciae latae-based perforators were used. There was one total flap loss on postoperative day 7 caused by recipient vessel spasm. One patient had partial necrosis of the distal portion of the flap with delayed healing. CONCLUSIONS: The anterolateral thigh flap is an excellent choice for massive defects requiring skin and soft-tissue coverage. The flap can be extended safely beyond the limit of 240 cm as suggested by cadaver perfusion studies. Inclusion of tensor fasciae latae perforators may increase the blood supply of the flap proximally; however, in general, a single perforator is capable of supplying a large area of the lateral thigh. Copyright © 2008 by the American Society of Plastic Surgeons.
Keywords: adult; clinical article; aged; aged, 80 and over; middle aged; surgical technique; anterolateral thigh flap; perforator flap; postoperative period; surgical flaps; outcome assessment; neoplasm; skin neoplasms; microsurgery; graft necrosis; patient identification; postoperative complications; wound healing; graft failure; ischemia; experience; clinical evaluation; tissue and organ harvesting; microcirculation; graft survival; wound healing impairment; soft tissue neoplasms; recipient; tensor fascia lata muscle; vasospasm
Journal Title: Plastic and Reconstructive Surgery
Volume: 122
Issue: 2
ISSN: 0032-1052
Publisher: Lippincott Williams & Wilkins  
Date Published: 2008-08-01
Start Page: 492
End Page: 496
Language: English
DOI: 10.1097/PRS.0b013e31817dc4c0
PUBMED: 18626367
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 10" - "Export Date: 17 November 2011" - "CODEN: PRSUA" - "Source: Scopus"
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MSK Authors
  1. Joseph Disa
    262 Disa
  2. Andrea Pusic
    300 Pusic
  3. Babak Mehrara
    448 Mehrara
  4. Peter G Cordeiro
    282 Cordeiro