Long-term psychosexual adjustment of acute leukemia survivors: Impact of marrow transplantation versus conventional chemotherapy Journal Article


Authors: Mumma, G. H.; Mashberg, D.; Lesko, L. M.
Article Title: Long-term psychosexual adjustment of acute leukemia survivors: Impact of marrow transplantation versus conventional chemotherapy
Abstract: Psychosexual sequelae associated with surviving acute leukemia treated with conventional chemotherapy or with chemotherapy followed by bone marrow transplantation (BMT) were investigated in 70 patients who were off treatment for at least 1 year. Assessment of psychosexual function included frequency of sexual activity, satisfaction, body image, gender role identity, and adjustment in sexual relations. No differences between BMT and conventional chemotherapy survivors were found on any of these measures, despite the high probability of gonadal impairment with BMT. Compared with physically healthy norms, women survivors generally reported decreased sexual frequency and satisfaction, whereas both men and women survivors reported poorer body image. Longer time since completing cancer treatment predicted greater frequency of sexual activity in women but poorer body image for both men and women. Those survivors who reported decreased sexual frequency, satisfaction, and poorer body image reported greater psychological distress and decreased energy. Results indicate that psychosexual sequelae in survivors of leukemia occur frequently and warrant intensive investigation, particularly to address the need for an intervention in those most distressed. © 1992.
Keywords: adolescent; adult; controlled study; leukemia; major clinical study; prednisone; doxorubicin; comparative study; chemotherapy; cytarabine; methotrexate; antineoplastic combined chemotherapy protocols; cyclophosphamide; vincristine; gonad dysfunction; questionnaires; adaptation, psychological; acute leukemia; sexuality; drug combination; daunorubicin; asparaginase; distress syndrome; cancer care facilities; new york city; interview; sex difference; drug therapy; sex factors; bone marrow transplantation; body image; tioguanine; sexual behavior; acute disease; personal satisfaction; psychosexual disorder; sexual dysfunctions, psychological; gender identity; human; male; female; priority journal; article; support, non-u.s. gov't; support, u.s. gov't, p.h.s.; sex behavior
Journal Title: General Hospital Psychiatry
Volume: 14
Issue: 1
ISSN: 0163-8343
Publisher: Elsevier Science, Inc.  
Date Published: 1992-01-01
Start Page: 43
End Page: 55
Language: English
DOI: 10.1016/0163-8343(92)90025-6
PUBMED: 1730401
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 30 July 2019 -- Source: Scopus
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  1. Lynna M. Lesko
    40 Lesko