Meningitis due to ß-hemolytic non-A, non-D streptococci among adults at a cancer hospital: Report of four cases and review Journal Article


Authors: Sepkowitz, K. A.; Kasemsri, T.; Brown, A. E.; Kiehn, T. E.; Armstrong, D.
Article Title: Meningitis due to ß-hemolytic non-A, non-D streptococci among adults at a cancer hospital: Report of four cases and review
Abstract: Four cases of meningitis due to ß-hetnolytic non-A, non-D streptococci among adult patients with neoplastic disease are reported. All four patients had head or neck tumors for?4 years, and all had undergone surgery for these tumors. Three of four patients had received local radiation therapy. None of the patients were neutropenic. One patient died. A review of the literature revealed that most patients with non-A, non-D streptotoccal meningitis had disruption of the normal barrier protecting the CNS due to trauma, surgery, or the presence of a tumor, or had extensive exposure to animals or an underlying medical disease. Infection with non-A, non-D streptococci should be considered in any patient with meningitis who has a tumor of the head or neck and who has undergone surgery and/or radiation therapy. © 1992, by The University of Chicago.
Keywords: adult; antibiotic agent; retrospective studies; clinical feature; mortality; case report; radiation; risk factor; cerebrospinal fluid; head and neck cancer; surgery; gentamicin; vancomycin; meningitis; tobramycin; streptococcal infections; bacterium isolation; middle age; clindamycin; streptomycin; cefazolin; kanamycin; blood culture; ampicillin; oxacillin; streptococcus; chloramphenicol; meningitis, bacterial; penicillin g; human; male; female; priority journal; article; nafcillin; cefalotin; sulfanilamide; hemolytic streptococcus
Journal Title: Clinical Infectious Diseases
Volume: 14
Issue: 1
ISSN: 1058-4838
Publisher: Oxford University Press  
Date Published: 1992-01-01
Start Page: 92
End Page: 97
Language: English
DOI: 10.1093/clinids/14.1.92
PUBMED: 1571468
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 30 July 2019 -- Source: Scopus
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  1. Kent A Sepkowitz
    272 Sepkowitz
  2. Timothy E Kiehn
    100 Kiehn
  3. Arthur E Brown
    76 Brown
  4. Donald Armstrong
    240 Armstrong