Recurrence patterns and outcome in 1019 patients undergoing axillary or inguinal lymphadenectomy for melanoma Conference Paper
| Authors: | Gadd, M. A.; Coit, D. G. |
| Title: | Recurrence patterns and outcome in 1019 patients undergoing axillary or inguinal lymphadenectomy for melanoma |
| Conference Title: | 45th Annual Cancer Symposium of the Society of Surgical Oncology |
| Abstract: | Patterns of recurrence and outcome were determined in 403 patients with melanoma who underwent an axillary or inguinal lymphadenectomy. Recurrences developed at single sites in 291 (72%) patients, with a median survival of 11 months, and at multiple sites in 112 (28%) patients, with a median survival of 3 months. Among patients with single-site recurrence, those with nonvisceral recurrence (n=190) had a median survival of 18.5 months compared with 6 months in those with visceral recurrence (n=101). Recurrences were treated surgically in 240 (60%) patients, with a median survival of 15 months, and nonsurgically in 112 patients, with a median survival of 4 months. Median survival after complete resection of single-site recurrence was 19 months compared with 6 months after incomplete resection. Multivariate analysis revealed that outcome was improved by surgical treatment, single-site and nonvisceral recurrence, and primary site in an extremity. These observations support an approach of selective resection in the treatment of recurrences after lymphadenectomy. © 1992, American Medical Association. All rights reserved. |
| Keywords: | adolescent; adult; cancer survival; treatment outcome; aged; aged, 80 and over; survival rate; major clinical study; cancer recurrence; conference paper; recurrence risk; lymph node metastasis; lymphatic metastasis; neoplasm staging; lymph node excision; lymphadenectomy; melanoma; skin neoplasms; recurrence; axillary lymph node; survival time; multivariate analysis; inguinal lymph node; axilla; middle age; groin; human; male; female; priority journal |
| Journal Title | Archives of Surgery |
| Volume: | 127 |
| Issue: | 12 |
| Conference Dates: | 1992 Mar 16-17 |
| Conference Location: | New York, NY |
| ISBN: | 0004-0010 |
| Publisher: | American Medical Association |
| Date Published: | 1992-12-01 |
| Start Page: | 1412 |
| End Page: | 1416 |
| Language: | English |
| DOI: | 10.1001/archsurg.1992.01420120046008 |
| PUBMED: | 1365686 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 30 July 2019 -- Source: Scopus |
