Radionuclide evaluation of the lower gastrointestinal tract Journal Article
| Authors: | Mariani, G.; Pauwels, E. K. J.; AlSharif, A.; Marchi, S.; Boni, G.; Barreca, M.; Bellini, M.; Grosso, M.; De Bortoli, N.; Mumolo, G.; Costa, F.; Rubello, D.; Strauss, H. W. |
| Article Title: | Radionuclide evaluation of the lower gastrointestinal tract |
| Abstract: | This review outlines the technical aspects and diagnostic performance parameters of nuclear medicine procedures used on patients with disorders of the lower gastrointestinal tract, with the exclusion of techniques using tumor-seeking radiopharmaceuticals. Chronic disorders of the lower gastrointestinal tract often reduce the quality of life because of discomfort from constipation or diarrhea. Five classes of radionuclide procedures are used to characterize these disorders: transit scintigraphy, searches for ectopic gastric mucosa in Meckel's diverticulum, scintigraphy of active inflammatory bowel disease, scintigraphic defecography, and scintigraphy to detect sites of gastrointestinal bleeding. Protocols for these procedures and their relative merit in patient management are discussed, with special emphasis on their potential for semiquantitative assessment of the pathophysiologic parameter investigated. Quantitation is particularly relevant for prognostic purposes and for monitoring the efficacy of therapy. Copyright © 2008 by the Society of Nuclear Medicine, Inc. |
| Keywords: | constipation; review; diarrhea; gastrointestinal hemorrhage; nonhuman; pathophysiology; positron emission tomography; technetium 99m; diagnostic procedure; quality of life; computer assisted tomography; digoxin; health care cost; iodine 131; colon cancer; fluorodeoxyglucose f 18; heparin; colon resection; enteritis; ulcerative colitis; feedback system; radioisotope; etidronic acid tc 99m; single photon emission computer tomography; indium 111; small intestine; metronidazole; gastrointestinal disease; calcium channel blocking agent; colon; radionuclide imaging; pentetate indium in 111; crohn disease; 8 quinolinol indium in 111; technetium sulfur colloid tc 99m; gastrointestinal tract scintiscanning; irritable colon; ranitidine; gastrointestinal; hemorrhage; gastrointestinal obstruction; laxative; dipyridamole; radionuclide; prokinetic agent; pertechnetic acid tc 99m; gi; transit scintigraphy; chloride in 111; hexamethylpropylene amine oxime technetium tc 99m; pentetate technetium tc 99m; propranolol; quinidine; defecography; lactose intolerance; meckel diverticulum; stomach emptying; lower gastrointestinal tract |
| Journal Title: | Journal of Nuclear Medicine |
| Volume: | 49 |
| Issue: | 5 |
| ISSN: | 0161-5505 |
| Publisher: | Society of Nuclear Medicine |
| Date Published: | 2008-05-01 |
| Start Page: | 776 |
| End Page: | 787 |
| Language: | English |
| DOI: | 10.2967/jnumed.107.040113 |
| PUBMED: | 18413380 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 4" - "Export Date: 17 November 2011" - "CODEN: JNMEA" - "Source: Scopus" |
