Melanonychia following mohs surgery for recurrent squamous cell carcinoma in situ of the nail bed Journal Article


Authors: Lipoff, J. B.; Scope, A.; Busam, K. J.; Nehal, K. S.
Article Title: Melanonychia following mohs surgery for recurrent squamous cell carcinoma in situ of the nail bed
Abstract: Background: Longitudinal melanonychia (LM) is characterized by the appearance of a longitudinal pigmented band in the nail plate. Melanonychia can occur from many causes, including racial predisposition, trauma, drugs, pregnancy, Addison disease, Peutz-Jeghers syndrome, Laugier-Hunziker syndrome, Bowen disease, onychomycosis, benign nail matrix nevi, and melanoma. Objective: We present a case of diffuse melanonychia developing several months following Mohs surgery for a human papillomavirus-induced recurrent squamous cell carcinoma in situ of the nail bed. Conclusions: This case illustrates the diagnostic dilemma in determining the etiology of the melanonychia and considers the differential diagnosis.
Keywords: adult; histopathology; case report; squamous cell carcinoma; carcinoma, squamous cell; drug withdrawal; adjuvant therapy; recurrent cancer; neoplasm recurrence, local; imiquimod; differential diagnosis; tumor biopsy; biopsy; epiluminescence microscopy; keratinocyte; carcinoma in situ; hyperpigmentation; nail bed; nail pigmentation; mohs surgery; chemosurgery; melanosis; wart virus; bowen disease; nail diseases; right handedness
Journal Title: Journal of Cutaneous Medicine and Surgery
Volume: 12
Issue: 4
ISSN: 1203-4754
Publisher: B C Decker Inc  
Date Published: 2008-07-01
Start Page: 194
End Page: 197
Language: English
DOI: 10.2310/7750.2008.07046
PUBMED: 18627701
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 1" - "Export Date: 17 November 2011" - "CODEN: JCMSF" - "Source: Scopus"
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MSK Authors
  1. Kishwer S Nehal
    278 Nehal
  2. Alon Scope
    125 Scope
  3. Klaus J Busam
    688 Busam
  4. Jules Benjamin Lipoff
    3 Lipoff
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