Detection of the dermis/epidermis boundary in reflectance confocal images using multi-scale classifier with adaptive texture features Conference Paper


Authors: Kurugol, S.; Dy, J.; Rajadhyaksha, M.; Brooks, D. H.
Title: Detection of the dermis/epidermis boundary in reflectance confocal images using multi-scale classifier with adaptive texture features
Conference Title: 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro
Abstract: Reflectance confocal microscopy is an emerging modality for dermatology applications, especially in-situ and bedside detection of skin cancers. Work to date has concentrated on hardware development and validation by clinicians in comparison with standard histological staining. As this technology gains acceptance, the development of automated processing methods becomes more important. We concentrate here on detection of the dominant internal feature of the skin, the epidermis/dermis boundary, a complex corrugated 3-dimensional layer marked by optically subtle changes and features. We adopt a machine learning approach to this segmentation problem, using a hierarchical multi-scale classifier with sophisticated on-line feature selection, to minimize the required expert labeling and maximize the range of potential features in the face of high inter- and intra-subject variability and low optical contrast. Initial results indicate the ability of our approach to recover the complex 3-D boundary surface. ©2008 IEEE.
Keywords: three dimensional; classification; confocal microscopy; skin; standardization; artificial intelligence; reflection; labeling; image segmentation; biomedical imaging; painting; boundary conditions; chlorine compounds; classification (of information); classifiers; computer networks; electromagnetic waves; microscopic examination; technical presentations; multi scaling
Journal Title International Symposium on Biomedical Imaging. Proceedings
Conference Dates: 2008 May 14-17
Conference Location: Paris, France
ISBN: 1945-7928
Publisher: IEEE  
Location: Paris
Date Published: 2008-06-13
Start Page: 492
End Page: 495
Language: English
DOI: 10.1109/ISBI.2008.4541040
PROVIDER: scopus
DOI/URL:
Notes: --- - "2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, Proceedings, ISBI" - "IEEE Int. Symp. Biomed. Imaging: Nano Macro, Proc., ISBI" - "Conference code: 73366" - "Cited By (since 1996): 2" - "Export Date: 17 November 2011" - "Art. No.: 4541040" - "Sponsors: Institute of Electrical and Electronic Engineers; Engineering in Medicine and Biology Society; Signal Processing Society" - 14 May 2008 through 17 May 2008 - "Source: Scopus"
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