Screening for colorectal cancer - To the editor Journal Article


Author: Winawer, S. J.
Article Title: Screening for colorectal cancer - To the editor
Abstract: To the Editor: We have three questions about the important fecal occult-blood screening study by Mandel et al. (May 13 issue)1. First, although mortality from colorectal cancer was significantly reduced in the annually screened group, it is not clear whether this gain can be attributed to the selective detection of cancer by screening or to an artifact of the very high rate of false positive results (occurring in 10 percent of those screened each year) and consequent numerous colonoscopies. According to the authors' data, about 10,000 colonoscopies or colorectal examinations were performed in this group of about 15,000 to... © 1993, Massachusetts Medical Society. All rights reserved.
Keywords: adult; aged; cancer risk; note; diagnostic accuracy; letter; colorectal cancer; cancer screening; mass screening; cancer mortality; colorectal neoplasms; cost effectiveness analysis; health care cost; medicare; economics; colonoscopy; colorectal tumor; colon polyp; occult blood; middle age; human; priority journal
Journal Title: New England Journal of Medicine
Volume: 329
Issue: 18
ISSN: 0028-4793
Publisher: Massachusetts Medical Society  
Date Published: 1993-10-28
Start Page: 1354
Language: English
PUBMED: 8413423
PROVIDER: scopus
DOI/URL:
Notes: For full correspondence, see DOI: 10.1056/NEJM199310283291813 -- Source: Scopus
Citation Impact
MSK Authors
  1. Sidney J Winawer
    274 Winawer